It has been known for some time that there is a decreased number of cells in parts of the brain of individuals with DS. A recent study has confirmed this decrease in embryos. In the brain region responsible for involuntary movements and fine motor coordination - the cerebellum - researchers in Italy have show that there is a reduction in the number of new cells born. There was no change in the number of cells dying (which is also a natural developmental process in some situations). The decrease in cells in the cerebellum is thought to contribute to the decrease in motor coordination seen in some individuals with DS.
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